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Oncogene 35 , 30373048 (2016)

Glutathione-based supplements Conventional glutathione supplements generally come in tablet , capsule or powder form

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By directly upregulating the expression of immunosuppressive genes (CD39, CD73, and CCR8) through H3K18la, lactate induces the conversion of CAR-T cells into an immunosuppressive phenotype resembling CAR-Tregs