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10.1021/acsbiomaterials.3c00146 20 ImD

J Biol Chem, 267(10): 6672-6679

[DOI] [PubMed] [Google Scholar] 419.Yu BP

Reactive oxygen and nitrogen species (ROS and RNS, respectively) and lipid peroxidation mediate M1 macrophage activation and the M2 to M1 transition

Moreover, in the CCl-induced rodent model of liver fibrosis, luteolin administration reduced p-AKT expression, leading to HSC apoptosis and attenuated collagen deposition [119]

Early research has explored its cytoprotective and healing properties, not just in the gut but across a wide spectrum of tissues, including tendons, ligaments, muscle, and even the nervous system