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After 14 and 28 days, the animals were sedated using ketamine hydrochloride (90 mg/kg) and xylazine hydrochloride (9 mg/kg), until we ensure the absence of corneal reflexes

Although NDDS have shown excellent capability in treating depression, their clinical application still faces several challenges: 1) Toxicity studies are incomplete 2) Inadequate characterization techniques 3) Lack of standardized norms and regulations

CrossRef C-reactive protein-triglyceride glucose index and heart failure in US adults from NHANES 20012010 Ningyi Cheng, Zhicheng Ma, Yukun Chen, Lei Jin, Liangwan Chen Scientific Reports.2025;[Epub] CrossRef The association between triglyceride glucose-waist height ratio index and cardiometabolic multimorbidity among Chinese middle-aged and older adults: a national prospective cohort study Longyan Lv, Ping Zhang, Xuerui Chen, Yan Gao Cardiovascular Diabetology.2025;[Epub] CrossRef Dexamethasone-induced insulin resistance impaired artemin levels in the hippocampus and altered behavioural patterns Hasan alkan Scripta Medica.2025

Body mass index (BMI) is not significantly different between cases and controls

1 Introduction Globally, knee osteoarthritis (KOA) is one of the most commonly occurring disabling conditions, affecting over 364 million adults (Li et al., 2024), and it is widely recognized as the most prevalent and representative form of osteoarthritis (OA)