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two yeast peroxiredoxins display oxidative stress-dependent switching from a peroxidase to a molecular chaperone function

[9] The Long R3 design pushes the same principle further: the Arg-for-Glu swap at position 3 removes a residue important for binding-protein contact, and the 13-residue N-terminal extension further perturbs the IGFBP interface

Ed.) 2010;63:10961099

10.1093/ajcn/81.1.243s 64 GemmaM.CintaB.MayteB.JuanF.-L.GerardP.SalvadM

While many factors regulate tumor angiogenesis, vascular endothelial growth factor (VEGF) appears to have a dominant role, inducing vascular permeability, endothelial cell proliferation and migration, and new blood vessel growth