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Gong, Z., Tas, E., Yakar, S

Fair skin is a prevalent aesthetic and cultural preference, particularly in many regions of Asia and Africa

Gong C, et al

Competing interests The authors declare that they had no competing interests

10.1038/s41586-024-08334-8 191 SunJ.RoyS

38,39 These failures may be attributed in part to flaws in study design, such as imbalance in patient baseline across treatment arms and lack of specific participant eligibility criteria, but may also be due to the structure of the agents themselves being less active in humans and presenting off-target toxicity