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Ent1 and Ent2 are APs with modular domain architecture, displaying an epsin N-terminal homology (ENTH) domain followed by unstructured regions containing several interaction motifs: two Ubiquitin Interaction Motifs (UIMs), two Asn-Pro-Phe motifs (NPF) responsible for interacting with EH (Eps-15 Homology) domains of Ede1, and a C-terminal CBM

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