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If patients respond well to thiopurines, routine full blood counts and liver function tests are recommended every 3 months throughout therapy ( Another concern over thiopurine therapy is an increased risk of malignancy, specifically lymphoproliferative disorder

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Since the cytosol contains high concentrations of glutathione and is, therefore, a reducing environment, proteins containing disulfide bonds, which are formed from oxidized cysteine residues, cannot be produced within it