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By integrating multilayered datasets from transcriptomics, proteomics, metabolomics, and CRISPR screens, ML approaches can construct predictive models of proteostasis dynamics, allowing researchers to visualize how stress propagates through cellular networks

doi: 10.1038/mp.2014.88 51

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Branched-chain amino acid restriction in Zucker-fatty rats improves muscle insulin sensitivity by enhancing efficiency of fatty acid oxidation and acyl-glycine export

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