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Also supporting the hypothesis of involvement of an oxidant stress in hyperhomocysteinemia-mediated vascular disorders, an increase in plasma and aortic thiobarbituric acid reactive substances was related to the occurrence of atherosclerotic lesions in animals fed a methionine-enriched diet (Matthias et al, 1996

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The pharmaceutical formulation disclosed herein may comprise hydroxypropyl-beta- cyclodextrin having an average molar substitution (MS) of about 0.92

These groups received intravenous treatments of PBS, oridonin, orid-liposome, orid-liposome-MAL, TLR2 pep-orid-liposome at a dose of 5 mg/kg, or PBS as control every other day

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