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Description

broader NO-system interplay summarized in review (Sikiric 2014)

Metabolism 39 , 4042 (1990)

RN: Writing review & editing, Writing original draft, Validation, Supervision, Funding acquisition, Formal analysis, Conceptualization

Abstract 128

Studies indicate that abnormalities in iron metabolism in gastric cancer cells, such as upregulation of TFR1 and dysregulated ferritin storage, significantly promote ferroptosis sensitivity, while ferroptosis inducers (such as Erastin and RSL3) can enhance chemotherapy sensitivity and reverse resistance by inhibiting GPX4 or system Xc-