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The primary genetic targets for treating ferroptosis may include p53, Gpx4, ACSL4, and Nrf2

Biochim Biophys Acta 1597:123132 Serre L, Vellieux FM, Medina M, Gomez-Moreno C, Fontecilla-Camps JC, Frey M (1996) X-ray structure of the ferredoxin:NADP+ reductase from the cyanobacteriumAnabaenaPCC 7119 at 1.8 resolution, and crystallographic studies of NADP+ binding at 2.25 resolution

As food is a major resource for folate, studies reported that low folate level due to unbalanced diet is associated with higher prevalence on schizophrenia, particularly in infants with maternal nutritional deficiency 11,93

As broad generalist herbivores, green peach aphids are exposed to a wide variety of toxic metabolites in the plants from which they are feeding

Clinical evidence shows that colon dialysis combined with Chinese herbal enema can treat chronic renal failure by reducing the serum creatinine level and delaying the progression of kidney disease [193]

Once excreted into the intestine, these compounds undergo further hydrolysis by gut microbiota to regenerate GA, which can then be reabsorbed, completing the enterohepatic circulation (Ploeger et al., 2001)