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Methods: A prospective analysis of the previously developed and validated NASH-CHECK (version 1.0) PROM in the real-world TARGET-NASH observational longitudinal cohort in patients enrolled in the US was performed from 2021-2023

N501Y is a mutant variant emerging from the United Kingdom, South Africa and Brazil 50

This binding mechanism, a bit like a lock (epitope) and key (paratope), or two puzzle pieces with the same unique pattern, enables them to interlock together