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Moreover, rather than damage to the palmar cutaneous branches of the median nerve and local free nerve endings, Vanhees et al proposed a biomechanical origin for pillar pain, citing the division of the flexor retinaculum as the primary cause

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This makes DSIP particularly relevant in experimental designs focused on integrated pathway behavior rather than isolated mechanisms such as receptor activation or gene expression control

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That regulators are sitting on it for patent or profit reasons