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Description

In this embodiment, a cyclobenzaprine analog is incorporated into a sol-gel matrix that is a solid at room temperature

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In obese Zucker rats, oral AOD-9604 at 500mcg/kg daily for 19 days reduced body weight gain by over 50% compared to controls

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Myocardial ischemia-reperfusion injury is one of the primary complications in the treatment of myocardial infarction

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Removing the first three amino acids reduces its binding to IGF-binding proteins, which normally trap IGF-1 in circulation

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