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This novel scoring system provides an effective tool for clinicians, holding great promise for guiding clinical management and improving patient outcomes

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Nevertheless, significantly reduced activity was observed for all tested substrates

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Accordingly, we found that TFE3-S is mostly located to the cytosol under control conditions and only translocated to the nucleus following mTORC1 inactivation with Torin-1 (Fig

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In contrast, adiponectin, which plays an essential role in insulin sensitivity (Reference Bagheri, Rashidlamir and Ashtary-Larky10) , is reduced, linking its role to insulin resistance and type 2 diabetes mellitus (Reference Sirico, Bianco and DAlicandro8)

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