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To manage the risk of elevated transaminase levels, assess ALT and AST: within one month prior to initiation of XENPOZYME, within 72 hours prior to any infusion during dose escalation, which includes the first 3 mg/kg dose, or prior to the next scheduled XENPOZYME infusion upon resuming treatment following a missed dose

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After cooling to 25 C and centrifugation at 25 C, 4,000 g for 10 min, the supernatant was collected