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Description

In some embodiments, the otic formulation or composition comprises about 8% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof

furthermore, this sex difference persisted in female Bmal1 knockout mice that displayed increased core infarct size compared to wild type females (Wiebking et al., 2013)

Research also points to DSIP influencing stress-related metabolic disturbances that shift mitochondrial respiration from oxygen-dependent to oxygen-independent pathways