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Estrogenic and androgenic activity of PCBs, their chlorinated metabolites and other endocrine disruptors estimated with two in vitro yeast assays

Genes regulating glycogen synthase kinase-3 (GSK-3), a pro-apoptotic (programed cell death) peptide and a functional opponent of proteins involved in neuronal plasticity development, differentiation, and cytoskeletal assembly, have also been implicated in bipolar etiology

Schnyder A, Huwyler J (2005) Drug transport to brain with targeted liposomes

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Regulator of cell death

The resultant increased levels of homocysteine have been demonstrated to be a significant risk factor for cardiovascular disease