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Apoptotic cell death in the cerebellum of mutant weaver and lurcher mice

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Apomorphine activates central dopamine pathways, while three PDE5 inhibitors cover fast onset, long duration, and high selectivity

The reagents that were used in this study are as follows: RSL3 (Sigma-Aldrich), erastin (Cayman Chemical), ML162 (Sigma-Aldrich), liproxstatin-1 (Sigma-Aldrich), BODIPY 581/591 C11 (Invitrogen), Liperfluo (Dojindo), tert -butyl hydroperoxide (Tokyo Chemical Industry), acridine orange (Nacalai Tesque), FerroOrange (Dojindo), Lyso-RhoNox (synthesized at Prof