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Secondly, multi-pathway modulation: by improving tissue oxygenation, modulating hypoxic response pathways, antioxidant therapy, immune modulation, and metabolic regulation, these approaches mitigate hypoxic tissue damage and inflammation, thereby inhibiting inflammatory reactions and metabolic alterations, ultimately alleviating the autoimmune pathological progression in AID patients

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The solutions were prepared by dilution of NycoPrep 1.15 with PBS

Therefore, intake of antioxidants or ROS modulators should be well controlled in order to avoid undesired effects during cancer treatment

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Geiger A, Stillinger FH, Rahman A (1979)