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The association remained the same when the researchers factored in the scores on physical performance tests

In the hypertrophied and failing heart, decreased myocardial capacity for fatty acid oxidation occurs, leading to enhanced cardiac glucose utilization through anaerobic glycolysis, pyruvate accumulation and lactate production

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3 The role of TMAO in various diseases and the therapeutic effects of traditional Chinese medicine Multiple studies have shown that TMAO is involved in the occurrence and development of various chronic diseases, including cardiovascular, digestive, neurological, kidney diseases, and metabolic disorders