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Activation of the support is accomplished by disulde exchange between the sulfhydryl groups on the support and pyridyl disulde, giving rise to the release of pyridyl-2-thione

Cancer cells utilize various oncogenic signaling pathways to activate OXPHOS to gain a survival advantage during anticancer therapy, thus posing a considerable therapeutic challenge

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33 , 905922.e906 (2021)

The molecular basis of this pathogenesis is well documented, as lipid-derived carbonyls such as MDA are known to display cytotoxic and mutagenic potential in the gastrointestinal tract (GIT) or in internal organs upon absorption (Esterbauer 1993)