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Boulais, E., Lachaine, R., Hatef, A

This progression from direct antimicrobial effectors to systemic signaling molecules underscores the functional diversification of AMPs in plant immunity, contributing not only to resistance against biotic stressors but also to enhanced tolerance of abiotic challenges

22,23 There are special cases where a peptide macrocycle contains multiple loops or is connected at multiple points within the peptide sequence, which are referred to as bicycles and tricycles (Fig

Research by David Sinclairs laboratory at Harvard and other leading aging research institutions has established sirtuins as central mediators of longevity pathways in model organisms

While necessary for purification and stability, high concentrations of some counter-ions, particularly TFA, can have their own biological effects (e.g., cytotoxicity in sensitive assays)