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bioRxiv , (2024)

2021;321:L485l489

It also encourages healthy nervous system function

In the STING pathway, dsDNA derived from pathogens or damaged cells serves as a substrate for the enzyme cGAS (cyclic GMP-AMP synthase) which produces the second messenger cyclic GMP-AMP (cGAMP) from ATP and GTP

Patients with MASH-driven cirrhosis were initially classified into three subtypes: MASH with diabetes mellitus (DM-MASH), MASH with overweight or obesity (obese-MASH), or MASH with lean/normal weight and at least two metabolic abnormalities (metabolic dysfunction-MASH)