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Persistent ferroptosis in alveolar and endothelial cells triggers pro-fibrotic signaling pathways, such as those involving TGF- and connective tissue growth factor (CTGF), which drive ECM deposition and fibroproliferation

(Francia) demuestran estimulacin de matriz extracelular en fibroblastos humanos

Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosis

Glutathione and other antioxidants neutralize free radicals, lower systemic inflammation, and promote cellular repair critical for managing chronic conditions long-term

It also regulates caspase-3 and Bcl-2 proteins to protect neurons from glutamate toxicity, thereby reducing the risk of ischemic stroke and brain damage [22]

Aberrant and sustained activation of NF-B is frequently associated with tumour proliferation, resistance to therapy, and poor clinical outcomes