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Homocysteine-lowering therapy may have some cardiovascular benefits following coronary interventions (11) , but does not appear to lower risk of further cardiovascular events including stroke (12) (13) (14)

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Vocal nodules can improve with voice rest but will recur when the voice user reengages the voice in the behaviors that led to the nodules

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These studies indicate the potential of utilizing the de novo pathway, a less extensively studied pathway, as a therapeutic strategy for metabolic diseases Barth syndrome is a rare disease caused by mutations in the tafazzin gene encoding for cardiolipin (CL), a phospholipid specific for the mitochondria 303

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