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doi: 10.1038/sj.onc.1210911 296 KayrakliogluNHoruluogluBKlinmanDM

Cyanocobalamin is indicated for Vitamin B12 deficiencies due to malabsorption which may be associated with the following conditions: Addisonian (pernicious) anemia Gastrointestinal pathology, dysfunction, or surgery, including gluten enteropathy or sprue, small bowel bacterial overgrowth, total or partial gastrectomy Fish tapeworm infestation Malignancy of pancreas or bowel Folic acid deficiency It may be possible to treat the underlying disease by surgical correction of anatomic lesions leading to small bowel bacterial overgrowth, expulsion of fish tapeworm, discontinuation of drugs leading to vitamin malabsorption (see Drug/Laboratory Test Interactions), use of a gluten-free diet in nontropical sprue, or administration of antibiotics in tropical sprue

115 SayyahiA.JahanshahiM.AminiH.SepehriH

The USC-Exo effectively ameliorate IRI-AKI, as evidenced by reduced serum markers, improved kidney morphology, and altered levels of ferroptosis-related factors through suppressing the expression of ACSL4 (Figure 4), a key contributor to ferroptosis, through a mechanism involving the interaction between TUG1 and RNA-binding protein SRSF1

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