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It is characterized by microglial activation and enhanced release of inflammatory factors, such as tumor necrosis factor (TNF-), IL-2, IL-10, IL-4, IL-6, and interferon , which contribute to neuronal injury and death [30, 31]

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Limitations in biomarker development and clinical translation: A major translational gap lies in the lack of stage-specific, ferroptosis-related biomarkers for predicting AKI-to-CKD progression