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Discovery and development of sorafenib: a multikinase inhibitor for treating cancer

10.1093/aje/kwq131 55

Canadian researchers report consistent improvements in grip strength, pain reduction, and range of motion within the first 2-3 weeks of use

Heinzelmann S, Bauer G

The primary endpoint was area under the cagrilintide plasma concentration curve from time zero extrapolated to infinity (AUC 0 ) from baseline (day 1) to day 36 (renal impairment study) or day 39 (hepatic impairment study)