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Nature Biotechnology 40(11):1624-1633, 2022

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aeruginosa ) showed the maximum resistance, while Saccharomyces cerevisiae ( S

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Chronic Acetaminophen Ingestion Can Improve Blood Glucose Control Although a toxic dose of acetaminophen (3 h following 500 mg APAP/kg body weight) can rapidly induce hyperglycemia (Hinson et al., 1984) and acute liver failure secondary to clinical acetaminophen overdose can further impair the peripheral uptake of glucose (Clark et al., 2001), recent animal studies have demonstrated that acetaminophen, when taken at lower dosages (2030 mg/kg body weight) exhibits an ability to lower blood glucose levels in several animal disease models, including diabetes, high-fat (HF) diet induced obesity, and aging

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