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Chronic proton pump inhibitor use is not associated with vitamin B12 deficiency: 132

In a trial on adult volunteers, this dose did not lead to a significant increase in serum vitamin B 12 levels when given thrice daily for one week

Although LA is targeted specifically to the GI tract due to its nonabsorbed nature, understanding how long various formulations of the drug take to reach specific regions within the small intestine and in therapeutically effective concentrations are crucial for its use in other clinical conditions

Important Information Treatment is provided only following a clinical assessment Not all patients will be suitable for injection therapy In some cases, further investigation (e.g

10.1113/jphysiol.2009.171603 57 HuangZ

The DVC consists of the area postrema (AP), a circumventricular organ that lies outside the bloodbrain barrier