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One hypothesis suggests that HHcy leads to increased oxidative stress in the vascular system [49]

DiGiovanni, J

doi: 10.1016/0006-291x(73)90657-8

257 Aging causes ROS accumulation

Glutathione, the most abundant cellular thiol, provides the major antioxidant defense mechanism in all mammalian cells by neutralizing toxic peroxides (e.g