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doi: 10.3109/10799893.2015.1108337

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Prolonged synaptic glutamate elevation causes excessive neuronal firing, which raises intracellular calcium levels and has subsequent neurotoxic effects

They constructed hollow gold nanospheres (HAuNS) to trigger severe ER stress, which were conjugated with ICG and modified by ER-targeting pardaxin (FAL)-peptide, together with an oxygen-delivering hemoglobin liposome (FAL-Hb lipo)

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