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Vitiligo usually involves loss or dysfunction of melanocytes, often through autoimmune mechanisms

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Clinical data, TTE, speckle tracking Echo and cardiac imaging, biomarkers (NT-proBNP, aldosterone, norepinephrine), and survival data were prospectively collected at presentation, and at 6 & 12 months

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However, no significant changes were observed in fibrosis scores, although there was a trend toward more patients in the combination and vitamin E groups having improved fibrosis stages than in the placebo group