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IGF-1 LR3 is altered at the N-terminus (the 13-residue extension) and at position 3 (the ER substitution), changes aimed at the IGFBP-binding region

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Rev Physiol Biochem Pharmacol 175:71102 Lyu H, Wang H, Li L et al (2020) Hepatocyte-specific deficiency of Nrf2 exacerbates carbon tetrachloride-induced liver fibrosis via aggravated hepatocyte injury and subsequent inflammatory and fibrogenic responses