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In our DR model, Epitalon treatment prevented HG-induced hypomethylation in ARPE-19 cells, as assessed by global 5 mC levels (Supplementary Fig

Research has shown that piperine enhances autophagic flux through activation of the P2RX4 receptor, facilitates autophagosome-lysosome fusion, and thereby accelerates autophagic degradation of pathological SNCA (alpha-synuclein), exerting a neuroprotective effect

PMID 6117662 DOI: 10.1016/s0022-5347(17)54666-2 Barrisford GW, Steele GS (2025): Acute urinary retention

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It promotes cell migration and proliferation at injury sites, reduces inflammation, and supports the formation of new blood vessels to deliver healing nutrients where theyre needed most

doi: 10.1016/j.bbrc.2019.08.165 122 GuoXWZhangHHuangJQWangSNLuYChengBet al