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A small number of participants were referred to the author with partial efficacy on amitriptyline or cyproheptadine, and when episodes resolved after increasing the dosage the families chose not to start one or both cofactors

Figure 7 In summary, the addition of cystine resulted in the up-regulation of SOS and OxyR genes

Recent high mortality events highlight the potential pulse of nutrients in a single season: in 1999, an unusual mortality event of gray whales was ~7 times higher than the annual mean