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In these conditions, the iron-binding capacity of serum transferrin is exceeded, resulting in low affinity complexes of iron with other plasma components (Porto and De Sousa, 2007

doi: 10.1111/ajd.13811 123 NammourS.El MobadderM.BrugneraA

185 Oxidative stress hypothesis During regular metabolic processes, the body produces reactive oxygen species (ROS), reactive nitrogen species, and other highly reactive and unstable substances