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Clemmons et al

doi: 10.1371/journal.ppat.1000758, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] Levitz S

& Lambeth, D

Mechanistically, cytosolic mtDNA is a potent activator of NLRP3, providing a direct molecular link between mitochondrial dysfunction and chronic inflammation in the brain [42, 107]