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3, free glutamate in the environment is transported into the cell by a specific transporter (glutamate/GABA antiporter), which leads to the decarboxylation of glutamate to GABA by GAD, in which intracellular H + ions are consumed 36,76,78

Understanding the causes of B12 deficiency, recognising its early signs, and seeking timely treatment can prevent serious complications

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Table 4 Potential genes that could be targeted in Egusi to develop resistance to diseases by genome editing

This finding redirected efforts toward studying mitochondrial dysfunction as a therapeutic target