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In our multivariable linear regression model, the GCLC rs1555903 SNP remained statistically significantly associated with the biomarkers of renal injury, but the magnitude of the regression coefficient decreased by 9.8% with eGFR ( value from 2.43 to 2.19) and by 7.5% with -2MCG ( value from 20.88 to 19.32) after adjustment for sex

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Interactions of retinoid binding proteins and enzymes in retinoid metabolism