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Saccharomyces boulardii administration changes gut microbiota and reduces hepatic steatosis, low-grade inflammation, and fat mass in obese and type 2 diabetic db/db mice

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Pin1 allows for differential tau dephosphorylation in neuronal cells

320 Similar protective roles are observed in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), where HSP70 and HSP90 suppress the aggregation of TDP-43, a protein that forms pathological cytoplasmic inclusions in affected neurons

Due to its defined mechanism and reproducible activity, 5-Amino-1MQ is commonly referenced in laboratory models exploring metabolic regulation, methyl donor balance, and NAD-related pathways