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Three pentacyclic triterpenes protect H9c2 cardiomyoblast cells against high-glucose-induced injury

Whether selective targeting of ferrous iron burden can impact on ageing and lifespan is unknown

This revealed an intriguing difference in LPS O-chain structure

Neuronal glucose uptake is predominantly facilitated by GLUT3, although other transporters such as GLUT2 and GLUT4 may be involved in glucose uptake into neurons under specific physiological or pathophysiological conditions (183)

Cancer cells exhibit heightened metabolic activity, resulting in elevated ROS levels compared to normal tissues, which drives persistent oxidative stress (Moloney and Cotter, 2018)