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THE TIME COURSE OF DRUG EFFECT The principles of pharmacokinetics (discussed in this chapter) and those of pharmacodynamics (discussed in Chapter 2 and Holford & Sheiner, 1981) provide a framework for understanding the time course of drug effect

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The first month I think has been kind of slow but Ive done this before and I know there will be more loss the second month

The assumption of a uniform diffusion coefficient for M2 macrophages oversimplifies biological tissues, which often exhibit variable diffusion properties due to differences in extracellular matrix composition and tissue stiffness 25,27

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