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Genesus, 2017

Cortisone was FDA approved for human use in 1949 after decades of trials and has been available every year ever since

Interestingly, improvements in glucose metabolism were observed in two studies that reported decreased oxidative stress markers (6, 23)

10.1016/j.fsi.2022.08.042 Fish Shellfish Immunol

Moreover, while most of the VR interventions included in this review were delivered in seated or low mobility settings and are therefore compatible with the use of assistive devices such as wheelchairs, few studies explicitly reported on participants with severe mobility limitations or advanced frailty

Therefore, while glutathione is generally considered safe, there can be potential side effects to be considered with its use