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Once in the circulation, LT4 is almost fully bound to plasma proteins

B.RosiniE.PollegioniL.VignaliE.HaidukowskiM.et al (2020)

cell 40 , 294309 (2010)

In addition to hormonal mechanisms, human data suggest sex-specific responses to ketogenic therapy for weight loss, with men often showing greater reductions in body mass and inflammation levels than women [73,89]