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Additional reference Sir Frederick Gowland Hopkins Sir Frederick Gowland Hopkins was awarded the Nobel Prize in Physiology or Medicine in 1929, with Christiaan Eijkman, for the discovery of vitamins

Significance levels are denoted as follows: * P -values 0.05

Following this, coverslips were blocked with 2% bovine serum albumin in PBS for 1 h at room temperature and subjected to immunofluorescence staining using an NFE2L2 antibody, followed by Alexa Fluor 488-conjugated IgG

10p), and GGsTop delivery in drinking water led to inhibition of GGT activity in animals and suppressed tumour growth (Extended Data Fig

26 , 16271640 e1627 (2019)

The ongoing ATLAS study in presymptomatic SOD1 carriers may provide further insights into whether early intervention can delay clinical onset