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However, they may reduce fatigue or decrease muscle soreness during and after exercise

Codapane 159

Kiemer AK, Bildner N, Weber NC, Vollmar AM

Circulating dopamine activates the Gs-cAMP-PKA pathway by binding to the D1R receptor on immune cells, further inhibiting NF-B and the NLRP3 inflammasome, reducing the levels of inflammatory factors such as TNF- and IL-1, and improving the systemic and pulmonary inflammatory responses (182)

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NADPH oxidase 2 (NOX2) is the key enzyme responsible for the cellular ROS production by using superoxide radicals (O 2 -) as precursor molecule [59]