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in some cases they are classified as superficial, deep, and plexiform,7 whereas in others they are divided into cutaneous, subcutaneous, and plexiform (nodular and diffuse).43 In actual fact, it is difficult to classify neurofibromas with exclusively clinical or histological criteria, as some lesions are not readily classified because of a mixed infiltrative pattern, more than 1 histological component, or histological and clinical transformations during their lifetime

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Biomolecules 10 , 550 (2020)