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10.1039/D0OB01358G 195 WuL.TangZ.ChenH.RenZ.DingQ.LiangK.et al

The role of vasculature and angiogenesis for the pathogenesis of degenerative tendons disease

Diverse cyclic di-nucleotides (CDNs, such as 23-cGAMP, 32-cGAMP, 23-c-di-AMP, 23-c-di-GMP) produced by cGLRs then interact with STING (240) which results in the activation of the NF-B transcription factor Relish through the kinase IKK which is part of the IMD innate immune pathway (241)